Histological responses of port wine stains in brown skin after 578 nm copper vapor laser treatment

Background. Granulomas of the vermilion border of the lips (GVBL); as a complication of lip tattooing; inevitably poses cosmetic problems. Surgical excision and cryodestruction are associated with an increased risk of scarring and recurrence of GVBL. Laser therapy can selectively destroy a pigment and achieve the desired cosmetic result with minimal risk of side effects. So laser treatment was reported to be a more relevant method of treatment of GVBL. Aim. To evaluate the effectiveness of treatment of GVBL with copper vapor laser (CVL) radiation. Case report. 39-year-old female patient; without manifestations of systemic sarcoidosis; reported a 2-year history of granulomas of the lips vermilion border. She had a permanent makeup cosmetic tattoo before the onset of granulomas after lip tattooing. Histopathological examination revealed the presence of pigment in the upper and middle layers of the dermis. GVBL treatment was performed using a CVL during a single procedure; with an average CVL power of 0.60.8 W; with a ratio of 3:2 at wavelengths of 511 nm and 578 nm; exposure time 0.3 s. Light spot diameter 1 mm. CVL treatment led to a pronounced elimination of all GVBL without side effects within five years. Discussion. CVL allows a combined mode of exposure; consisting of grinding large granules of pigment to sizes that can be absorbed by the lymphatic system and suppressing VEGF expression using radiation with a wavelength of 578 nm. Conclusions. The CVL treatment provided an excellent cosmetic result due to selective photodestruction of the pigment and complete remodeling of the vascular bed associated with GVBL. The high clinical efficiency of eliminating post-tattooing foci of GVBL using CVL without side effects allows us to suggest this method for dermatologists and cosmetologists as a highly effective and inexpensive way to eliminate complications of permanent makeup.

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Numerical optimization of the dual-wavelengths copper vapor laser treatment of basal cell cancer

XIV International Conference on Pulsed Lasers and Laser Applications ◽

10.1117/12.2553321 ◽

2019 ◽

Author(s):

Igor Ponomarev ◽

Sergey . Topchiy ◽

Mishik . Kazaryan ◽

Aleksandra. E. Pushkareva ◽

Svetlana V. Klyuchareva ◽

...

Keyword(s):

Laser Treatment ◽

Basal Cell ◽

Numerical Optimization ◽

Cell Cancer ◽

Copper Vapor Laser ◽

Vapor Laser ◽

Basal Cell Cancer ◽

Copper Vapor

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Treatment of pyogenic granuloma with copper vapor laser radiation

Vestnik dermatologii i venerologii ◽

10.25208/vdv1209 ◽

2021 ◽

Vol 97 (2) ◽

pp. 41-49

Author(s):

Igor V. Ponomarev ◽

Ludmila D. Shakina ◽

Sergey B. Topchiy ◽

Svetlana V. Klyuchareva ◽

Alexandra E. Pushkareva

Keyword(s):

Clinical Practice ◽

Side Effects ◽

Laser Treatment ◽

Postoperative Bleeding ◽

Pyogenic Granuloma ◽

Copper Vapor Laser ◽

Surgical Removal ◽

Vapor Laser ◽

Copper Vapor ◽

The Face

Background. Pyogenic granuloma (PG) or lobular capillary hemangioma, ICD10 code: L98.0. appears as a single bright red or violet papule up to 20 mm in size, on the face, fingers, skull surface, arms, and intergluteal fold, as well as on the oral mucous membranes. Surgical removal of facial PG is not always possible due to insufficient thickness of the dermis. Treatment of PG with a pulsed dye laser (PDL) or neodymium laser (Nd:YAG) can achieve a noticeable elimination of the lesion but is reported to be accompanied by such side effects as purpura or scarring. It determines the feasibility of introducing into clinical practice the methods of laser treatment of PG using the radiation of a copper vapor laser (CVL) with a wavelength of 578 nm, which effectively absorbed by the blood. Aim. The assessment of the clinical efficacy and safety of the CVL treating PG. Methods. 26 adult patients with PG in various parts of the face, including the lips, limbs, and trunk, were included in this study. PG treatment was carried out in one session with CVL (Yakhroma-Med, FIAN) at an average power of 0.71.0 W, at a wavelength of 578 nm, exposure time 0.20.3 s. The diameter of the light spot is 1 mm. Results. Immediately after the single laser treatment, the PG involved area became grey. In 710 days, the irradiated area was utterly similar to the adjacent intact skin. No postoperative bleeding or infection was noted. Side effects included mild skin atrophy. During the follow-up observation for five years, no side effects were found. Conclusion. The high efficiency of PG elimination using CVL in the absence of pronounced side effects allows suggesting this method for introducing into dermatologists and cosmetologists' clinical practice as a highly effective and inexpensive method of treatment.

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Numerical simulation of port-wine stain blood vessel selective heating using a copper vapor laser with a scanner

Laser Physics ◽

10.1088/1555-6611/ab0369 ◽

2019 ◽

Vol 29 (4) ◽

pp. 045601 ◽

Cited By ~ 2

Author(s):

I V Ponomarev ◽

S B Topchiy ◽

A E Pushkareva ◽

S V Klyuchareva

Keyword(s):

Numerical Simulation ◽

Blood Vessel ◽

Copper Vapor Laser ◽

Port Wine Stain ◽

Port Wine ◽

Vapor Laser ◽

Selective Heating ◽

Copper Vapor

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Treatment of Basal Cell Cancer With a Pulsed Copper Vapor Laser: A Case Series

Journal of lasers in medical sciences ◽

10.15171/jlms.2019.57 ◽

2019 ◽

Vol 10 (4) ◽

pp. 350-354

Author(s):

Svetlana V. Klyuchareva ◽

Igor V. Ponomarev ◽

Sergey B. Topchiy ◽

Alexandra E. Pushkareva ◽

Yury N. Andrusenko

Keyword(s):

Side Effects ◽

Laser Treatment ◽

Histological Examination ◽

Basal Cell ◽

Cell Cancer ◽

Case Series ◽

Copper Vapor Laser ◽

Vapor Laser ◽

Copper Vapor ◽

Ocular Injuries

Introduction: Basal cell carcinoma (BCC) is the most prevalent form of non-melanoma skin cancer commonly arising in elderly patients. Currently, many laser systems are applied for the treatment of BCC. However, up to the present, there have been several reports concerning ocular side effects due to the laser procedure in the borders of the periorbital area. This determines the feasibility of testing new laser surgical modes for the management of periorbital BCC. This stuay aimed to estimate both the efficacy, the early post-radiated side effects and long-term outcomes of the CVL treatment of periorbital BCC. Patients and Methods: Two men and 6 women aged 50 to 77 years were diagnosed with periorbital BCC according to the data of both the clinical evaluation and histological examination of the tissue samples taken from the involved area. Six months after the laser treatment, the histological examination of skin samples from the borderline of the irradiated area was made again. All patients were followed for 24 months after the laser treatment of BCC. The laser treatment was administered during one session of copper vapor laser (CVL) (Yakhroma-Med model). The treatment included CVL radiation with a wavelength of 511 nm and 578 nm, in the ratio of 3:2. The power level was set up to 3 W, and the exposure time was equal from 200 to 600 ms. The pulse duration accounted for 15 ns. The diameter of the light spot on the skin surface amounted to 1 mm. Results: Dual-wavelengths CVL treatment of periorbital BCC provided a complete elimination of malignant cells and dysplastic vessels during one procedure. The duration of skin healing amounted to 2-4 weeks. There were neither ocular injuries or pronounced skin side effects nor relapses within 24 months after the laser procedure. Conclusion: CVL treatment of periorbital BCC provides relevant cosmetic results without ocular injuries and relapses.

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